Deep mineral resources need to be discovered and accessed to ensure the ever increasing needs of minerals in our society. Seismic methods have proven their capacity to image important targets in deep, crystalline environments, but their use is not yet a standard within conventional mineral exploration activities. The EIT-RawMaterials Programme has funded the “Seismic Imaging for Mineral Exploration – SIT4ME” project, aimed to develop seismic imaging approaches for mineral exploration within crystalline settings, at a reduced cost. The aim of this transnational initiative is to test the efficiency of seismic methods to image target ore structures by comparing control and natural source seismic data-sets in two real case-studies, the Zinkgruvan mine in Sweden and the Sotiel mine in Spain. This work describes the main objectives and activities carried out as part of the project, and outlines the expected outcomes of this initiative.